Investigating the adverse effects related with long term use of paracetamol

Guidelines often recommend paracetamol as a first-line analgesic, particularly for osteoarthritis (OA), based on its perceived safety. However, there is growing discussion, highlighted in the National Institute for Health and Care Excellence OA (NICE) 2014 guidance on OA, that paracetamol is not as safe as originally thought, especially at the highest therapeutic dose of 4gm/day. …

Chronic Pain and Work

The aim of this study is to develop a toolkit for employees with chronic pain. This toolkit will address the barriers to working for people who experience pain, encouraging self-management through promoting physical and mental wellbeing.  It will provide advice on adjustments to work environments in order to create a more inclusive and accessible environment. …

How hand osteoarthritis is associated with hand pain and function

Dr Abhishek is currently leading a study that investigates ultrasound markers of symptoms of hand osteoarthritis (OA). OA is the most prevalent form of arthritis, particularly concerning hand joints. The symptoms of OA include; joint swelling, functional impairment, participation restriction and overall reduced quality of life. Despite this, there are no disease-modifying drugs for OA …

Investigating Musculoskeletal Health and Wellbeing Newsletter

The Investigating Musculoskeletal Health and Wellbeing Newsletter is an annual newsletter keeping you up to date with news from the study and studies linked with it. Here you’ll find some highlights from our community of studies and events.

Muscle mass, metabolic quality and physical function in frail older people with non-weight bearing fractures.

“No decline with age is as dramatic or potentially more significant than the decline in lean body mass” (1). In 1989 Rosenberg published this observation and coined the term sarcopenia, a description that has subsequently been extended to incorporate the associated loss of muscle strength and function (2, 3). Muscle loss begins in the fifth …

KNEE OSTEOARTHRITIS AND WEB-BASED EXERCISES

“Helping research is not only about helping yourself but about helping the generations to come. And it does not stop there, as the research, in which you helped, may facilitate or initiate many other studies. It is like a chain reaction and credit go to all the volunteers helping with these studies.” Sameer Gohir   …

The Benefits of a Nurse-Led Package of Care for Knee Pain and Osteoarthritis

Nottingham’s Biomedical Research Centre are currently in the midst of an exciting new study, titled ‘The East-Midlands Knee Pain Multiple Randomised Controlled Trial Cohort Study: Cohort Establishment and Feasibility cohort-randomised controlled trial’. Led by Chief Investigator Dr Abhishek, Clinical Associate Professor of Rheumatology, the study is set to develop a nurse-led package of care for …

Investigating Musculoskeletal Health and Wellbeing Cohort Study

The NIHR Nottingham Biomedical Research Centre is currently recruiting for a study investigating Musculoskeletal Health and Wellbeing, led by Professor David Walsh. This research is being funded by NIHR and Versus Arthritis. Professor David Walsh himself is a consultant rheumatologist, who first became interested in a career in rheumatology because of the exciting research taking …

The Musculoskeletal Theme Annual Science Day

The Musculoskeletal Theme Annual Science Day took place on the 14th January and brought together students, researchers, clinicians, academics and all those interested in MSK research in Nottingham. The opening session was led by the Phenotyping Research Area which featured a presentation on the Investigating Musculoskeletal Health and Wellbeing Cohort Study, a 5 year longitudinal …