Investigating the adverse effects related with long term use of paracetamol

Guidelines often recommend paracetamol as a first-line analgesic, particularly for osteoarthritis (OA), based on its perceived safety. However, there is growing discussion, highlighted in the National Institute for Health and Care Excellence OA (NICE) 2014 guidance on OA, that paracetamol is not as safe as originally thought, especially at the highest therapeutic dose of 4gm/day. …

How hand osteoarthritis is associated with hand pain and function

Dr Abhishek is currently leading a study that investigates ultrasound markers of symptoms of hand osteoarthritis (OA). OA is the most prevalent form of arthritis, particularly concerning hand joints. The symptoms of OA include; joint swelling, functional impairment, participation restriction and overall reduced quality of life. Despite this, there are no disease-modifying drugs for OA …

The truth behind the pubic rami fracture: identification of pelvic fragility fractures at a university teaching hospital

Dawn van Berkel, O Herschkovich, R Taylor, Terence Ong, Opinder Sahota Health Care of the Older Persons, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK Older patients presenting with pelvic fragility fractures(PFF) is an increasing epidemic. The most common pelvic fracture identified by plain radiograph is pubic rami fracture. These fractures are painful …

Investigating Musculoskeletal Health and Wellbeing Newsletter

The Investigating Musculoskeletal Health and Wellbeing Newsletter is an annual newsletter keeping you up to date with news from the study and studies linked with it. Here you’ll find some highlights from our community of studies and events.

Muscle mass, metabolic quality and physical function in frail older people with non-weight bearing fractures.

“No decline with age is as dramatic or potentially more significant than the decline in lean body mass” (1). In 1989 Rosenberg published this observation and coined the term sarcopenia, a description that has subsequently been extended to incorporate the associated loss of muscle strength and function (2, 3). Muscle loss begins in the fifth …

Investigating Musculoskeletal Health and Wellbeing Cohort Study

The NIHR Nottingham Biomedical Research Centre is currently recruiting for a study investigating Musculoskeletal Health and Wellbeing, led by Professor David Walsh. This research is being funded by NIHR and Versus Arthritis. Professor David Walsh himself is a consultant rheumatologist, who first became interested in a career in rheumatology because of the exciting research taking …

The Musculoskeletal Theme Annual Science Day

The Musculoskeletal Theme Annual Science Day took place on the 14th January and brought together students, researchers, clinicians, academics and all those interested in MSK research in Nottingham. The opening session was led by the Phenotyping Research Area which featured a presentation on the Investigating Musculoskeletal Health and Wellbeing Cohort Study, a 5 year longitudinal …