Investigating Musculoskeletal Health and Wellbeing Newsletter

The Investigating Musculoskeletal Health and Wellbeing Newsletter is an annual newsletter keeping you up to date with news from the study and studies linked with it. Here you’ll find some highlights from our current projects and the results of our research.

Investigating Musculoskeletal Health and Wellbeing Newsletter

A BIG THANK YOU TO THOSE WHO HAVE BEEN CONTRIBUTING TO OUR RESEARCH. YOUR INVOLVEMENT AND CONTINUED SUPPORT IS VALUABLE AND GREATLY APPRECIATED. To find out more about our research please follow the link below: Newsletter

Persistent knee pain following total knee replacement

The problem of knee Osteoarthritis (OA), and therefore chronic pain and disability, is on the rise. Although total knee replacement (TKR) has significantly improved pain and functioning for most end-stage knee OA patients, unfortunately 20% of patients still report persistent knee pain following TKR. Third year medical student, Lauren Quinn, undertook a project which aimed …

Identifying key elements of non-pharmacological treatment package for fibromyalgia: Evidence synthesis and Delphi exercise

Fibromyalgia (FM) is a long-term condition that causes pain all over the body and currently has no cure. However, there are treatments which can help relieve some of the symptoms and make the condition easier to live with. Burak Kundakci, a PhD student at the University of Nottingham, conducted research into a package of care …

Investigating the adverse effects related with long term use of paracetamol

Guidelines often recommend paracetamol as a first-line analgesic, particularly for osteoarthritis (OA), based on its perceived safety. However, there is growing discussion, highlighted in the National Institute for Health and Care Excellence OA (NICE) 2014 guidance on OA, that paracetamol is not as safe as originally thought, especially at the highest therapeutic dose of 4gm/day. …

My Experience as Communication Co-ordinator

I was successful in gaining a placement as the Communication Co-ordinator for the NIHR Nottingham Biomedical Research Centre (BRC) MSK Theme, based in the Department of Academic Rheumatology for the spring semester through the School of English placements scheme. Throughout my time here I have been responsible for a number of tasks ranging from involvement …

Effectiveness of inactivated influenza vaccine in autoimmune rheumatic diseases, treated with disease-modifying anti-rheumatic drugs

Researchers at Nottingham University report that seasonal flu vaccine protects from flu and its complications in people with inflammatory conditions treated with immune suppressing medicines. Influenza causes 291,000-650,000 deaths per year globally. Overall, it is estimated to cause 3.1 million hospitalized days and 31.4 million outpatient visits that costs the USA economy 87.1 billion dollars …

Neural adaptations to acute muscle damage in younger and older adults (AMD)

Muscle force relies on a combination of altered motor unit (MU) firing rates and recruitment through an increasing range of sizes. However, alterations in these mechanisms may influence muscle functional decline when in a fatigued and damaged state. Although eccentric exercise provokes more significant loss of function, muscle damage and soreness than concentric exercise, it …

Chronic Pain and Work

The aim of this study is to develop a toolkit for employees with chronic pain. This toolkit will address the barriers to working for people who experience pain, encouraging self-management through promoting physical and mental wellbeing.  It will provide advice on adjustments to work environments in order to create a more inclusive and accessible environment. …

How hand osteoarthritis is associated with hand pain and function

Dr Abhishek is currently leading a study that investigates ultrasound markers of symptoms of hand osteoarthritis (OA). OA is the most prevalent form of arthritis, particularly concerning hand joints. The symptoms of OA include; joint swelling, functional impairment, participation restriction and overall reduced quality of life. Despite this, there are no disease-modifying drugs for OA …