Effectiveness of inactivated influenza vaccine in autoimmune rheumatic diseases, treated with disease-modifying anti-rheumatic drugs

Researchers at Nottingham University report that seasonal flu vaccine protects from flu and its complications in people with inflammatory conditions treated with immune suppressing medicines. Influenza causes 291,000-650,000 deaths per year globally. Overall, it is estimated to cause 3.1 million hospitalized days and 31.4 million outpatient visits that costs the USA economy 87.1 billion dollars …

Neural adaptations to acute muscle damage in younger and older adults (AMD)

Muscle force relies on a combination of altered motor unit (MU) firing rates and recruitment through an increasing range of sizes. However, alterations in these mechanisms may influence muscle functional decline when in a fatigued and damaged state. Although eccentric exercise provokes more significant loss of function, muscle damage and soreness than concentric exercise, it …

Chronic Pain and Work

The aim of this study is to develop a toolkit for employees with chronic pain. This toolkit will address the barriers to working for people who experience pain, encouraging self-management through promoting physical and mental wellbeing.  It will provide advice on adjustments to work environments in order to create a more inclusive and accessible environment. …

How hand osteoarthritis is associated with hand pain and function

Dr Abhishek is currently leading a study that investigates ultrasound markers of symptoms of hand osteoarthritis (OA). OA is the most prevalent form of arthritis, particularly concerning hand joints. The symptoms of OA include; joint swelling, functional impairment, participation restriction and overall reduced quality of life. Despite this, there are no disease-modifying drugs for OA …

The truth behind the pubic rami fracture: identification of pelvic fragility fractures at a university teaching hospital

Dawn van Berkel, O Herschkovich, R Taylor, Terence Ong, Opinder Sahota Health Care of the Older Persons, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK Older patients presenting with pelvic fragility fractures(PFF) is an increasing epidemic. The most common pelvic fracture identified by plain radiograph is pubic rami fracture. These fractures are painful …

Investigating Musculoskeletal Health and Wellbeing Newsletter

The Investigating Musculoskeletal Health and Wellbeing Newsletter is an annual newsletter keeping you up to date with news from the study and studies linked with it. Here you’ll find some highlights from our community of studies and events.

How lying in bed will help future manned missions to Mars

  Scientists at the University of Nottingham are helping to push back the boundaries of space travel in a new study to examine a potentially serious adverse effect of weightlessness on the human body.   The 3-day bed rest study is being carried out in Nottingham in parallel to a 60-day bed rest study currently …

Muscle mass, metabolic quality and physical function in frail older people with non-weight bearing fractures.

“No decline with age is as dramatic or potentially more significant than the decline in lean body mass” (1). In 1989 Rosenberg published this observation and coined the term sarcopenia, a description that has subsequently been extended to incorporate the associated loss of muscle strength and function (2, 3). Muscle loss begins in the fifth …

KNEE OSTEOARTHRITIS AND WEB-BASED EXERCISES

“Helping research is not only about helping yourself but about helping the generations to come. And it does not stop there, as the research, in which you helped, may facilitate or initiate many other studies. It is like a chain reaction and credit go to all the volunteers helping with these studies.” Sameer Gohir   …

The Benefits of a Nurse-Led Package of Care for Knee Pain and Osteoarthritis

Nottingham’s Biomedical Research Centre are currently in the midst of an exciting new study, titled ‘The East-Midlands Knee Pain Multiple Randomised Controlled Trial Cohort Study: Cohort Establishment and Feasibility cohort-randomised controlled trial’. Led by Chief Investigator Dr Abhishek, Clinical Associate Professor of Rheumatology, the study is set to develop a nurse-led package of care for …