Gene drives and Trojan horses: A tale of two metaphor uses
February 28, 2020
I was reading a recent article on gene drive entitled “Engineering bugs, resurrecting species: The wild world of synthetic biology for conservation” and came across this sentence about a so-called ‘Medea drive’: “This genetic Trojan Horse could then be used to spread elements that confer susceptibility to certain environmental factors, such as triggering the death …
Heritable Genome Editing: National and international governance challenges and policy options
July 27, 2019
This blog post has been co-authored with Achim Rosemann (University of Exeter). A shorter and slightly different version has been published by the BioMed Central ‘On Society’ Blog. *** Germline gene editing has become a hot topic in science and in society, after one Chinese scientist edited embryos in 2018, an experiment that a Russian …
CRISPR culture
March 15, 2019
CRISPR is a way of changing and replacing parts of DNA using enzymes like a pair of molecular scissors (of course things are more complex than this!). This new technology for ‘editing’ DNA, genes or genomes began to attract public attention between around 2012 and 2015. When I started to write about metaphors used to …
Making science by publicity stunt: The case of the CRISPR babies
November 29, 2018
Science is supposed to be a public, systematic, consensible, evidence-based and collaborative enterprise. It’s also supposed to be carried out responsibly, not recklessly. Making science in public and making science public are complex processes. Making public science normally doesn’t consist in presenting fellow-scientists and members of the public with a ‘fait accompli’. This is however …
Genome editing: Invisible mending
December 1, 2017
Last week I had a few days in Oxford to visit old haunts, such as the Ashmolean, the Museum of Natural History and the Pitt Rivers Museum. I also went to a little exhibition in the basement of the Museum of the History of Science. The exhibition by Anna Dumitriu was entitled BioArt and Bacteria. …
Base editing, biological complexity and the limits of metaphorical explanation
October 2, 2017
Gene editing has been in the news since around 2013. Here I want to focus on one of the most recent advances which made me question my own understanding of gene editing. In 2015 a team of scientists led by Junjiu Huang at Sun Yet-Sen University in Guangzhou, China, used gene editing techniques, in this …
CRISPR, unicorns and responsible language use
June 23, 2017
I was looking through my twitter timeline on 12 June, when I came cross a tweet by Dietram Scheufele which said “’bend nature to our will.’ #CRISPR frame in new #Doudna book might resonate differently across audiences […] #scicomm”. The tweet made reference to an article by Sharon Begley in STAT News about Jennifer Doudna’s new book, co-authored with Samuel Sternberg, A …
Do metaphors really matter?
June 16, 2017
I, like many others, from Leibniz to Lakoff, think that metaphors are important for human thinking and acting. They make us see the world in different ways – for good or evil. So, one should keep an eye on them. Recently I have read two articles which seem to imply that metaphors matter less than …
CRISPR and genome editing: Real and imagined
October 28, 2016
For several years now there has been a buzz around a new advance in genomics called genome (or gene) editing. “Genome editing is the deliberate alteration of a selected DNA sequence in a living cell.” Scientists have been able to do gene editing for a while, but to find and replace any sequence in any …
CRISPR – and the race is on (again)
July 25, 2016
At the weekend I was reading an article in the Guardian about a team of Chinese scientists trying to use CRISPR/gene editing for the treatment of cancer; and I sighed. The article contained some of the standard and, I believe, quite worn-out tropes that pepper coverage of advances in biotechnology: playing God, designer babies…, as …
MSP bookmarks
- Twitter May 8, 2017
- Social innovations in Europe #RRI November 3, 2015
- Harvey Graff, the undisciplinarian September 20, 2015
- Replacing Pesticides With Genetics August 31, 2015
- Addressing hazardous chemicals in the circular economy August 25, 2015
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