Gene drives and Trojan horses: A tale of two metaphor uses
February 28, 2020
I was reading a recent article on gene drive entitled “Engineering bugs, resurrecting species: The wild world of synthetic biology for conservation” and came across this sentence about a so-called ‘Medea drive’: “This genetic Trojan Horse could then be used to spread elements that confer susceptibility to certain environmental factors, such as triggering the death …
Engineering biology? Sure! But which kind?
February 7, 2020
This is a guest post by Massimiliano Simons who is a postdoctoral researcher at the department of philosophy and moral sciences at Ghent University, Belgium. *** Biology is a mess, not only the natural processes out there but also the science in the lab. Every biological rule seems to have exceptions and all biological laboratories …
Xenobots-Xenowhats? Living machines and zombie metaphors
January 24, 2020
The other day a colleague asked me what I was up to. I said, ‘I am starting to think about xenobots’. ‘Xeno-whats?’ he asked? I muttered something like ‘you know as in ‘xeno-transplantation’, when another colleague butted in and asked ‘like Xenogenesis?’. ‘Xeno-what?’ I asked. It turns out there is a sci-fi trilogy by Octavia E. Butler written in the …
A road called ‘gene drive’ and the road to ‘gene drive’: Trials and tribulations of media analysis
October 25, 2019
As people might know, I enjoy doing media analysis of emerging biotechnologies, from cloning to gene editing and beyond. I have lately become fascinated with something called ‘gene drive’, a new genetic engineering technology that was brought to public attention around 2014/2015 at the confluence of two ‘events’: the outbreak of Zika and advances in CRISPR-Cas9 …
The microbe/gene drive communication confusion
September 27, 2019
Last week I wrote a post about how genetic modification and/or gene drive are used when managing disease transmitting insects. I want to come back to this topic today and talk about another difference, which, yet again, confused me. I hope that these efforts of disentangling stuff also help other people trying to understand and …
The GM/gene drive communication confusion
September 20, 2019
The other day, I was at the airport waiting for a plane back to the UK, when I noticed on twitter that there was some kerfuffle going on about a field trial in Brazil intended to eliminate disease carrying mosquitoes, which had had, it seems, some unintended consequences (see study). Here is a short summary: …
Heritable Genome Editing: National and international governance challenges and policy options
July 27, 2019
This blog post has been co-authored with Achim Rosemann (University of Exeter). A shorter and slightly different version has been published by the BioMed Central ‘On Society’ Blog. *** Germline gene editing has become a hot topic in science and in society, after one Chinese scientist edited embryos in 2018, an experiment that a Russian …
Metaphors, machines and the meaning of life
June 30, 2019
Machine metaphors are ubiquitous in biology, nowhere more so than in synthetic biology, a type of biology that is inspired by engineering and design. This has attracted the attention of metaphor analysts, but also of philosophers and ethicists. Various scholars, both from the humanities/social sciences and the life sciences have grappled with some of the …
Mice, dice and copycats: Metaphors for gene drives in mammals
February 8, 2019
When you hear the word ‘gene drive’, you will either be baffled or you will think about mosquitoes, engineered to eradicate insect-born disease like malaria, Dengue fever, or Zika for example. But gene drive research has now moved from insects to mammals. Mammals On the 23rd of January, researchers at University of California, San Diego, …
Gene drive communication: Obstacles and opportunities
January 18, 2019
The other day I was talking to two people about various developments in science. Both are interested in science, but they are not natural scientists. I mentioned ‘gene drives’. Their faces went blank. I then said: “it’s something like the gene editing of a whole population of creatures, such as insects, for example. This can …
MSP bookmarks
- Twitter May 8, 2017
- Social innovations in Europe #RRI November 3, 2015
- Harvey Graff, the undisciplinarian September 20, 2015
- Replacing Pesticides With Genetics August 31, 2015
- Addressing hazardous chemicals in the circular economy August 25, 2015
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