Hybrids and chimeras: Mythology, history and science

Last week two papers were published about human and other chimeras, one in Cell on ‘Interspecies chimerism with mammalian pluripotent stem cells’ and one in Nature entitled ‘Interspecies organogenesis generates autologous functional islets’. The first one caused a bit of a stir in the newspapers. About 70 newspaper articles covered this potential scientific breakthrough in All …

Gene editing, metaphors and responsible language use

Last week I was following the progress of the International Summit on Human Gene Editing, which took place in Washington between 1 and 3 December, 2015. On the last day, I was looking at my twitter timeline and saw that Megan Allyse (a former PhD student) had posted information on a special issue devoted to …

The book of life: Reading, writing and editing

I have been observing the use of the ‘book of life’ metaphor in genetics and genomics since the year 2000, when it was used to announce that the human genome, our entire DNA, had been roughly sequenced. The Human Genome Project had begun in 1990 and was completed in 2003. Its achievement consisted in finding …

Dark matter: A mystery metaphor that turns genomic junk into gold

I have become intrigued by a new metaphor, most recently used in an interesting Aeon Magazine article. The authors state that the human genome can’t be, as was so long assumed, a blueprint for building a human being, as “science has served up the confounding paradox that the bulk of our genome appears to be …