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Epigenetics, hype and harm

I first became interested in epigenetics in around 2010/2011. I know this because I trawled my emails and found a link that I had sent myself on 11 February 2011 to an article in Mother Jones entitled “The illustrated guide to epigenetics”. The first paragraph of this guide is rather prophetic: “This month marks the …

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Assembling a synthetic human genome: Science and the politics of openness

There has recently been some commotion in the field of synthetic biology about a meeting held at Harvard on 10 May 2016 at which scientists discussed the creation of a synthetic human genome. The meeting was a closed, invitation-only meeting. In a field of science that takes pride in its openness and transparency, this created …

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Musings on language and life, with special reference to ‘programming’

This morning I opened the newspaper and read an article about a new language that lets researchers design novel biological circuits. I mumbled something about this over coffee and my husband said, oh but wasn’t that old hat, we all knew that DNA was a language, code etc. So what was new? I looked again …

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Synthetic biology, metaphors and ethics: An emerging topic of international interest

As some of you know, I have been interested in metaphors for a long time and more recently have become intrigued by metaphors used when talking about synthetic biology, gene drives, gene editing and so on. This has led to a meeting in Cambridge (Downing College) between Steven Burgess, who edits the PLOS Synbio community …

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Precision metaphors in a messy biological world

The promises of nanoscience and nanotechnology have been framed by a variety of future oriented metaphors, such as the those of the fantastic voyage or the master builder. The former metaphor has been especially prominent in early reports on the promises of nanomedicine, but it is still in use today. What happens when real breakthroughs …

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‘Pathways’ in science and society

“Two roads diverged in a yellow wood; And sorry I could not travel both; And be one traveler, Long I stood, And looked down one as far as I could, To where it bent in the undergrowth.” (Robert Frost, 1916) I have walked along many paths, even pathways, on my journey through life. Recently, I …

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On books, circuits and life

I have recently been trying to understand CRISPR, gene editing and genome editing. While reading about these new developments in genomics, I noticed that in the avalanche of news reports reference is only rarely made to synthetic biology (on 5 January there were 188 articles on CRISPR in Major World Newspapers on the LexisNexis news …

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Gene editing, metaphors and responsible language use

Last week I was following the progress of the International Summit on Human Gene Editing, which took place in Washington between 1 and 3 December, 2015. On the last day, I was looking at my twitter timeline and saw that Megan Allyse (a former PhD student) had posted information on a special issue devoted to …

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The book of life: Reading, writing and editing

I have been observing the use of the ‘book of life’ metaphor in genetics and genomics since the year 2000, when it was used to announce that the human genome, our entire DNA, had been roughly sequenced. The Human Genome Project had begun in 1990 and was completed in 2003. Its achievement consisted in finding …

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The colours of biotechnology

I have recently been musing about images used to make science public and wondered what images are out there for synthetic biology. I knew that in the past cloning was visually represented by ‘Dolly the sheep’ or ‘armies of little Hitlers’, nano found its visual incarnation in nanobots and fantastic voyage, but what images would …

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