Search for "genomics"

Epigenetics, hype and woo

A couple of weeks ago I noticed a new twitter account: @EpigeneticsBs (short for ‘epigenetics bullshit’). Its mission is to make epigenetic ‘bullshit’ public, or as it says: “There’s a lot of #epigenetics pseudoscience & quackery out there. We RT some of it for your edification and entertainment.” These (re)tweets are produced by people working …

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CRISPR and genome editing: Real and imagined

For several years now there has been a buzz around a new advance in genomics called genome (or gene) editing. “Genome editing is the deliberate alteration of a selected DNA sequence in a living cell.” Scientists have been able to do gene editing for a while, but to find and replace any sequence in any …

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The Institute for Science and Society: Past, present, future

Many of you will have seen a new video of the brilliant work done at the Faculty of Social Sciences here at the University of Nottingham since about 1948. I was looking at this during my last days as Director of the Making Science Public programme and also through the eyes of a co-founder of …

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The epigenetic muddle and the trouble with science writing

I have been interested in epigenetics, especially public portrayals of epigenetics, for about six or seven years. About three years ago I tried to get some funding to examine emerging and changing meanings of epigenetics in traditional and new media (including what one might call ‘alternative’ media), but unfortunately never got the funding. When writing …

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CRISPR – and the race is on (again)

At the weekend I was reading an article in the Guardian about a team of Chinese scientists trying to use CRISPR/gene editing for the treatment of cancer; and I sighed. The article contained some of the standard and, I believe, quite worn-out tropes that pepper coverage of advances in biotechnology: playing God, designer babies…, as …

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Epigenetics, hype and harm

I first became interested in epigenetics in around 2010/2011. I know this because I trawled my emails and found a link that I had sent myself on 11 February 2011 to an article in Mother Jones entitled “The illustrated guide to epigenetics”. The first paragraph of this guide is rather prophetic: “This month marks the …

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Assembling a synthetic human genome: Science and the politics of openness

There has recently been some commotion in the field of synthetic biology about a meeting held at Harvard on 10 May 2016 at which scientists discussed the creation of a synthetic human genome. The meeting was a closed, invitation-only meeting. In a field of science that takes pride in its openness and transparency, this created …

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Musings on language and life, with special reference to ‘programming’

This morning I opened the newspaper and read an article about a new language that lets researchers design novel biological circuits. I mumbled something about this over coffee and my husband said, oh but wasn’t that old hat, we all knew that DNA was a language, code etc. So what was new? I looked again …

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Synthetic biology, metaphors and ethics: An emerging topic of international interest

As some of you know, I have been interested in metaphors for a long time and more recently have become intrigued by metaphors used when talking about synthetic biology, gene drives, gene editing and so on. This has led to a meeting in Cambridge (Downing College) between Steven Burgess, who edits the PLOS Synbio community …

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Precision metaphors in a messy biological world

The promises of nanoscience and nanotechnology have been framed by a variety of future oriented metaphors, such as the those of the fantastic voyage or the master builder. The former metaphor has been especially prominent in early reports on the promises of nanomedicine, but it is still in use today. What happens when real breakthroughs …

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