Search for "synthetic biology"

Gene drives and Trojan horses: A tale of two metaphor uses

I was reading a recent article on gene drive entitled “Engineering bugs, resurrecting species: The wild world of synthetic biology for conservation” and came across this sentence about a so-called ‘Medea drive’: “This genetic Trojan Horse could then be used to spread elements that confer susceptibility to certain environmental factors, such as triggering the death …

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Making Science Public 2019: An overview

Every year I think: This will be the last year I write something for this blog… and each year I write a bit more. And so it was this year. Whether that’s a good thing or a bad thing, I really don’t know. But it distracts me from life’s increasing troubles and keeps me sane. …

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Astrogenomics: Integration and inspiration

I should have blogged about embryo editing in Russia. I should have blogged about Netflix’s ‘Unnatural selection’ series on CRISPR and genome editing. I should have blogged about prime editing, but life is getting in the way at the moment. That doesn’t mean I don’t look at twitter once in a while (au contraire!). So, …

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The microbe/gene drive communication confusion

Last week I wrote a post about how genetic modification and/or gene drive are used when managing disease transmitting insects. I want to come back to this topic today and talk about another difference, which, yet again, confused me. I hope that these efforts of disentangling stuff also help other people trying to understand and …

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Inspecting Pandora’s box: Promises and perils of gene drives

This is a guest post by Aleksandra Stelmach, University of Nottingham, Institute for Science and Society. *** Some years ago the sociologist Alan Petersen noted that metaphors of new biotechnologies not only express hopes and fears about their use and misuse, but that they also set the agenda for debate and action. Thus, metaphors not …

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Metaphors, machines and the meaning of life

Machine metaphors are ubiquitous in biology, nowhere more so than in synthetic biology, a type of biology that is inspired by engineering and design. This has attracted the attention of metaphor analysts, but also of philosophers and ethicists. Various scholars, both from the humanities/social sciences and the life sciences have grappled with some of the …

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New genetics and society: A retrospective

I am in a collecting mood at the moment [I have updated this collection/blog post on 17 January 2022 and on 8 October 2024]. When I heard that an article (with Carmen McLeod and Rusi Jaspal) on faecal microbial transplants had finally been accepted by New Genetics and Society, I began to count back and …

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Epigenetics: A blogging retrospective

Looking back over my blog posts, I realised that I have written 15 posts on epigenetics between 2013 and now (some with Aleksandra Stelmach). It’s time to take stock. Epigenetics is the latest in a long line of developments in genetics and genomics that I have studied through the lens of metaphor analysis, from cloning …

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Science and Metaphors

Today I gave a lecture on responsible innovation and responsible language use (via Skype) to biochem and synbio students at the University of Oxford. After the lecture, one student asked whether there was a good go-to book on science and metaphor. I hummed and hawed…. There is of course some stuff, but not a really …

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