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Mitochondrial replacement and the pangenome

Recently two events caught my attention, which should at least be noted on this blog: the publication of the first human pangenome on 10 May 2023 and the birth of babies through a new human fertilisation technique variously known as mitochondrial donation, mitochondrial transfer, mitochondrial transplant or mitochondrial replacement on 12 May. I’ll say a …

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The Gmelin family: From chemistry to phlogiston and permafrost

I had Covid. I was lying in bed. I saw a tweet by Mark Carnal saying: “Historians of Biology. How on earth is Gmelin pronounced? I’ve not had to say it out loud before.” I am not a historian of biology but, as a German speaker, I was intrigued. So, I looked up the name …

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Gene editing, gene shears and other titbits from the history of genetic engineering

I was wondering what to write about. In past blogs, I have done quite a bit of ‘conceptual history’ about metaphors or phrases like ‘imaginaries’, ‘tipping points’, ‘deficit model’, ‘trickle down economics’ and even ‘gene surgery‘ and ‘gene drive’. I have also written a few posts about gene editing or genome editing. But, come to …

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Chatting with a chatbot about metaphor

A week ago my son sent me a link to a tweet in which Ethan Mollick did a little experiment with one of the currently fashionable AI chatbots, a common pastime nowadays. He asked “Bing to look up Tamarian, a made-up Star Trek language that works entirely by metaphors to Tamarian history and myth. Then …

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Human genome editing summit, London, 2023

Ceci n’est pas un blog post. As I have no time to write anything proper for a few weeks, these are just some notes and pointers. This non-post is ‘about’ the Third International Summit on Human Genome Editing which took place at The Francis Crick Institute in London from 6 to 8 March. I couldn’t …

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Can metaphors hinder scientific progress?

This is a guest post by Jack Morgan Jones. He is a postgraduate researcher at the University of Manchester’s Philosophy Department with an interest in truth and practical rationality, as well as agency and constructivism. *** It’s readily acknowledged that metaphors can help an educated public better understand a scientist’s technical work. But questioning the …

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Bird flu – then and now

Current news about a world-wide bird flu outbreak brought back memories of 2005, dubbed then “The year of bird flu”. In an article I co-authored that year with Christopher Halliday, we noted that “[l]ately, fear of disease has been fuelled yet again by the emergence of a new highly pathogenic virus strain of avian influenza …

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Climate change and health: Early and late warnings

Last week I saw various tweets from the Wellcome Trust announcing a new funding scheme that will support research on the impacts of #ClimateChange on human health, centring on communities most at risk (an announcement that by the way, was illustrated with a tryptic of photos of lone individuals dealing with a flood, a fire …

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Knitting with hyperlinks: A decade of blogging

Ten years ago, I was walking down the corridor in the School of Sociology and Social Policy building, when I bumped into Adrian Mateo, who was then Faculty marketing manager. I knew him from various engagement events related to projects I was involved in at the time. We chatted a bit and he suddenly asked …

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Gene drive communication: On bombs and bullets

In a recent article for Scientific American, the zoologist and author of a recent book on the history of genetic engineering, Matthew Cobb, lays out the pros and cons of ‘gene drive’. Gene drive is a new genetic technology that could be used to wipe out whole species of insects that transmit, for example, malaria. …

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