Search for "\"gene editing\""

Mice, dice and copycats: Metaphors for gene drives in mammals

When you hear the word ‘gene drive’, you will either be baffled or you will think about mosquitoes, engineered to eradicate insect-born disease like malaria, Dengue fever, or Zika for example. But gene drive research has now moved from insects to mammals. Mammals On the 23rd of January, researchers at University of California, San Diego, …

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Gene drive communication: Obstacles and opportunities

The other day I was talking to two people about various developments in science. Both are interested in science, but they are not natural scientists. I mentioned ‘gene drives’. Their faces went blank. I then said: “it’s something like the gene editing of a whole population of creatures, such as insects, for example. This can …

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Science, life and meaning

Sheila Jasanoff has published a new book entitled Can Science Make Sense of Life? This is a big question to which the answer, according to Betteridge’s law of headlines must be ‘no’. The title sets the tone for the book and opens up specific expectations for its readers. What expectations readers have depends on what they understand …

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Blueprint, a broken metaphor?

Three things came together that made me write this post: observing an increased discussion of the blueprint metaphor in genetics and genomics around the publication of a book called Blueprint, reading an old article by George Gamow, and reading a footnote in a forthcoming book by Philip Ball entitled How to Build a Human. The …

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In the shadow of Frankenstein: Mapping and manipulating genes and genomes

I was starting to prepare a talk for Pint of Science in May, for “The Body” strand, which this year here in Nottingham focuses on regenerative medicine and genetic engineering. It’s entitled “GMYou”. I know, it’s a long way off, but they needed a title and so I began to muse. In the end I …

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Genome editing: Invisible mending

Last week I had a few days in Oxford to visit old haunts, such as the Ashmolean, the Museum of Natural History and the Pitt Rivers Museum. I also went to a little exhibition in the basement of the Museum of the History of Science. The exhibition by Anna Dumitriu was entitled BioArt and Bacteria. …

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Base editing, biological complexity and the limits of metaphorical explanation

Gene editing has been in the news since around 2013. Here I want to focus on one of the most recent advances which made me question my own understanding of gene editing. In 2015 a team of scientists led by Junjiu Huang at Sun Yet-Sen University in Guangzhou, China, used gene editing techniques, in this …

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Designer babies? Not again!

Preface: I had just put the finishing touches to this post and I was doing the washing up, when I heard on the six o’clock news that the paper I’ll talk about below has now been published in Nature. I’ll still publish this post though. It would be great to compare the pre-paper news coverage with the …

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