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CRISPR and genome editing: Real and imagined
October 28, 2016
For several years now there has been a buzz around a new advance in genomics called genome (or gene) editing. “Genome editing is the deliberate alteration of a selected DNA sequence in a living cell.” Scientists have been able to do gene editing for a while, but to find and replace any sequence in any …
CRISPR – and the race is on (again)
July 25, 2016
At the weekend I was reading an article in the Guardian about a team of Chinese scientists trying to use CRISPR/gene editing for the treatment of cancer; and I sighed. The article contained some of the standard and, I believe, quite worn-out tropes that pepper coverage of advances in biotechnology: playing God, designer babies…, as …
The book of life: Reading, writing and editing
November 22, 2015
I have been observing the use of the ‘book of life’ metaphor in genetics and genomics since the year 2000, when it was used to announce that the human genome, our entire DNA, had been roughly sequenced. The Human Genome Project had begun in 1990 and was completed in 2003. Its achievement consisted in finding …
Ta(l)king responsibility
May 28, 2015
In social science and policy circles there has been a lot of talk about Responsible Research and Innovation (RRI). However, nobody quite knows yet what this means and how it works in the context of harsh economic realities. In the meantime, natural scientists have taken responsibility for their research and innovations in the context of …
From recombinant DNA to genome editing: A history of responsible innovation?
March 24, 2015
In this post I shall report on a recent call for ethical and regulatory reflection by scientists engaged in a new genomic technology. I’ll then put this into a historical context of previous initiatives of that kind, and finally ask whether this can be called ‘Responsible Research and Innovation’. CRISPR Recently, a new controversy has …
Making science public: A compilation of blog posts – 2014
December 19, 2014
It is time again for my end of year blog of blog posts. Unbelievably, this is already the third time I am doing this. How time flies! Strange — so far we haven’t had a post about time! This is quite surprising, as otherwise we have had posts about more or less everything under the …
CRISPR, unicorns and responsible language use
June 23, 2017
I was looking through my twitter timeline on 12 June, when I came cross a tweet by Dietram Scheufele which said “’bend nature to our will.’ #CRISPR frame in new #Doudna book might resonate differently across audiences […] #scicomm”. The tweet made reference to an article by Sharon Begley in STAT News about Jennifer Doudna’s new book, co-authored with Samuel Sternberg, A …
‘See through science’
August 25, 2012
I was recently reminiscing about Venice, where I have been many times, soaking up the sunshine, the colours and little miracles in glass (about which more later). So I started to think about science and glass, and the title of a famous 2005 booklet produced by James Wilsdon and Rebecca Willis popped into my head: …