Mice, dice and copycats: Metaphors for gene drives in mammals

When you hear the word ‘gene drive’, you will either be baffled or you will think about mosquitoes, engineered to eradicate insect-born disease like malaria, Dengue fever, or Zika for example. But gene drive research has now moved from insects to mammals. Mammals On the 23rd of January, researchers at University of California, San Diego, …

Epigenetics: Grappling with definitions

Definitions of epigenetics are notoriously slippery. This does not seem to hamper basic research. But it might hamper public understanding. The words ‘epigenetics’ and ‘epigenetic’ have undergone quite substantial changes in meaning over time, leading up to a meaning which is now popular but open to misinterpretation. This history and increasing confusion has been charted, …

Synthetic biology: Modelling joys and fears brick by brick

Carmen McLeod, Stevienna de Saille and I recently published an article in which we used findings from a LEGO® SERIOUS PLAY® workshop to show that scientists’ (synthetic biologists’) views of risk and responsibility are much more ‘societal’ than one might expect. This means, involving them in a new form of science governance (RRI), which itself involves new …

Bacteria, metaphors and responsible language use

A lot has been written about the war on bacteria, especially in the context of antimicrobial resistance. Some articles reflect on the metaphor of war in medicine and in microbiology more generally, others deal with the metaphors of bacterial communication and communities. A few papers look more closely at the way bacteria are anthropomorphised in the …

Genome editing, metaphors and language choices

Genetic Alliance and the Progress Educational Trust recently published a report entitled ‘’Basic understanding of genome editing”, based on research supported by the Wellcome Trust. As I have worked on metaphors relating to genetic, genomics and genome editing for more than twenty years, I was particularly interested in this report. Unlike many other publications, including …

SBRC symposium: Synbio, metaphors and responsibility

On Monday this week (22 May, 2017) our Synthetic Biology Research Centre symposium on metaphors, synthetic biology and responsibility took place at the East Midlands Conference Centre at the University of Nottingham. The weather was marvellous and showed off University Park in all is spring glory. We started with a pre-conference dinner which, in a way, …

Building bridges in mind, language and society

On 2 January Mo Costandi tweeted: “’Be the neurotransmitter in your world. Diffuse ideas & human connections.’ Talking, the new world changing concept”. The quote within the tweet was taken from an article by David Rowan, Editor of Wired, in response to the 2017 question posed by Edge: What scientific term or concept ought to …

Precision metaphors in a messy biological world

The promises of nanoscience and nanotechnology have been framed by a variety of future oriented metaphors, such as the those of the fantastic voyage or the master builder. The former metaphor has been especially prominent in early reports on the promises of nanomedicine, but it is still in use today. What happens when real breakthroughs …

Gene editing, metaphors and responsible language use

Last week I was following the progress of the International Summit on Human Gene Editing, which took place in Washington between 1 and 3 December, 2015. On the last day, I was looking at my twitter timeline and saw that Megan Allyse (a former PhD student) had posted information on a special issue devoted to …

Dark matter: A mystery metaphor that turns genomic junk into gold

I have become intrigued by a new metaphor, most recently used in an interesting Aeon Magazine article. The authors state that the human genome can’t be, as was so long assumed, a blueprint for building a human being, as “science has served up the confounding paradox that the bulk of our genome appears to be …