// Latest Posts

Plague in the UK!

Researchers at the University of Nottingham thought that they had discovered an occurrences of the bacteria that causes plague in a rats from Liverpool and Vancouver. They were using a widely used microarray based platform specifically designed to identify zoonotic pathogens. By supplementing their analysis with metagenomics sequencing we were able to interrogate the validity …

Increasing lean muscle mass in pigs

Researchers at the University of Nottingham in conjunction with scientist at Zoetis were comparing the effect of growth hormones and beta agonists on pig growth. By integrating time series RNAseq, microarray and metabolomic datasets using machine learning we were able to identify some the key gene networks and enriched molecular pathways that could in part …

Why won’t that tomato ripen?

Researchers at the University of Nottingham in conjunction with scientist at Syngenta recently crossed the commercial tomato variety S. lypocosum with the wild cultivar S.pennellii. One of the intergression lines that was generated (with a block of S.pennellii DNA transposed into the coding region of chromosome 2) had an interesting fruit ripening phenotype and merited …

Health Data Research UK

Health Data Research UK (HDR UK) is the national Institute for data science in healthcare. By harnessing health and biomedical data in the UK, HDR UK will develop and apply cutting edge data science approaches to address the most pressing health research challenges facing the public. HDR UK is a joint investment led by the …

Supporting European Biobanks

The UKCRC Tissue Directory and Coordination Centre acts as the UK’s national node for the Biobanking and Biomolecular Resources Research Infrastructure – European Research Infrastructure Consortium (BBMRI-ERIC) which aims to establish, operate and develop a pan-European distributed research infrastructure of biobanks and biomolecular resources to facilitate the access to resources as well as facilities and …

UK Tissue Directory and Coordination Centre

Improving access to biobank data Human tissue samples are collected across the UK, yet the ability for researchers to undertake the necessary research into human conditions is still hampered by the inability to find suitable samples. The UK Clinical Research Collaboration (UKCRC) Tissue Directory and Coordination Centre was set up to support the work of …

Digital Data in Cancer Research

Effective collaboration and data management using OneNote Associate Professor Alan McIntyre (School of Medicine) leads a research group that studies the effects of hypoxia (low levels of oxygen) in the context of molecular and cell biology, with a focus on cancerous tumours. The research generates large amounts of raw and processed data in multiple formats. …

Simulating drug-induced changes in an easy to deploy software service

Containerising and scaling applications using Kubernetes and Azure Dr Gary Mirams is a Wellcome Trust Senior Research Fellow and member of the Centre for Mathematical Medicine & Biology (CMMB) in the School of Mathematical Sciences, where he constructs mathematical and computational models to describe biological processes. Mathematical models offer a way to describe the evolution …

Locating Ancient Trees

Mapping ancient trees using high performance computing Ancient trees are ecologically, historically and culturally important, and although we know the locations of many, there are plenty more to be discovered. Victoria Nolan, a PhD candidate at the University of Nottingham is using mathematical models to produce predictions of likely suitable areas for ancient trees allowing …

Generating Insights from Big Data

The analysis of ‘Big Data’ is one of the main challenges faced today by both academia and industry. The project titled Value Enhancement for Data from Assets & Transactions (VEDAT), which was carried out in partnership with the ASAP group in the School of Computer Science aimed to “provide tools that enable intelligent, predictive modelling …